Piko-tarou will improvise the story of each three-minute episode using an illustration by the anime's director Takashi Taniguchi. He will tell each story in the style of a fairy tale and voice every character, including himself. (Source: ANN)

The story revolves around Tomoya Mizuhara, a 13-year-old boy who suddenly gains a big sister when his father remarries. 17-year-old Ichika is a little strange, and her affection for Tomoya is rather overwhelming, if not scary. On top of things, Ichika's friend Ruri is the ultimate sadist. Then there is Ichika's big-breasted quarter-Japanese friend Marina. (Source: ANN)

Every 12 years, mercenaries who possess the highest caliber of brute strength, cunning wit, and deadly precision gather to participate in the Zodiac Tournament. Each warrior bears the name and attributes of one of the 12 animals of the Chinese zodiac. With their pride and lives on the line, they engage in vicious combat until only the victor remains. The 12th Zodiac Tournament begins in a desolate city, devoid of any evidence of the half million people who recently lived there. To raise the stakes, each warrior ingests a poisonous gem, thus setting a time limit on the tournament—and on their life. With one wish for the victor up for grabs, the Zodiac Warriors start their cutthroat battle for survival. [Written by MAL Rewrite]

The rare and inexplicable Puberty Syndrome is thought of as a myth. It is a rare disease which only affects teenagers, and its symptoms are so supernatural that hardly anyone recognizes it as a legitimate occurrence. However, high school student Sakuta Azusagawa knows from personal experience that it is very much real, and happens to be quite prevalent in his school. Mai Sakurajima is a third-year high school student who gained fame in her youth as a child actress, but recently halted her promising career for reasons unknown to the public. With an air of unapproachability, she is well known throughout the school, but none dare interact with her—that is until Sakuta sees her wandering the library in a bunny girl costume. Despite the getup, no one seems to notice her, and after confronting her, he realizes that she is another victim of Puberty Syndrome. As Sakuta tries to help Mai through her predicament, his actions bring him into contact with more girls afflicted with the elusive disease. [Written by MAL Rewrite]