Manji is an infamous swordsman in feudal Japan who is known as the "Hundred Man Killer," as he has killed one hundred innocent men. However, there is something far more frightening than his ominous reputation: the fact that he is immortal. This is the handiwork of eight-hundred-year-old nun Yaobikuni, who placed bloodworms capable of healing almost any wound in Manji's body. To atone for his crimes, Manji resolves to kill one thousand evil men. Yaobikuni agrees to this proposal, saying that if he succeeds, she will undo his curse of immortality. Soon after this promise, Manji meets Rin Asano, a 16-year-old girl who requests Manji's assistance in killing those who slaughtered her parents. Initially reluctant, Manji refuses Rin's desperate plea. However, owing to her evident lack of strength, Manji changes his mind and agrees to protect Rin for four years. With this partnership set in stone, the two embark on a perilous journey of bloodshed, vengeance, and redemption, each to fulfill their own life's cause.

Doraemon and its friends open a hole in the time and they're travel to the Country of Mayana, a lost Mayan civilization in the jungle. There, Nobita will know its perfect double, prince Thio, heir to the throne. Both will decide to interchange papers to try to save to the Country of Mayana of the claws of the infernal Ledina witch and her evil forces. (Source: ANN)

Despite the Ends’ attack on Verlina being successfully repelled, the war has not yet ended. With the monster armies regrouping, the Black King tightens his grasp on the already conquered territory. New conflicts erupt all across Orte, as its remaining forces struggle to retain control over long-oppressed demi-human races. While Ends grow more potent each day, Toyohisa Shimazu remains unconscious after heavy injuries suffered during the Battle of Verlina. Facing enemies on every side, humanity’s fate is still on a knife's edge.

The entire countryside comes to a halt midday to witness a rare solar eclipse that is rumored to allow the average person to see Mushi. Unable to avert their gaze, the air is full of awe and wonder—but those who know the Mushi are preparing for the eclipse's aftermath. Based on a prediction from Tanyuu Karibusa, the cursed recorder, Mushishi Ginko finds himself in a very unlucky farming village. Immediately following the solar eclipse, a strange black cloud begins to gather in the sky and blocks the sun once more. Suspecting it to be the work of a Mushi known as Hihami, Ginko seeks to liberate the village from perpetual darkness. However, it seems that not all of the villagers are eager to return to the light.