Year 202X. Self-driving electric cars have replaced internal combustion engine-based cars, becoming ubiquitous in Japan. However, a racing circuit known as MFG, which employs traditional internal combustion cars, is garnering popularity worldwide. Kanata Livington, a 19-year-old Japanese-British racer, comes to Japan after graduating from a top racing school in the United Kingdom to take part in MFG and find his missing father, Ken Katagiri. Kanata moves to the home of his late mother's friends—Mr. and Mrs. Saionji—and enters the race under his father's surname, borrowing a Toyota 86 from Ogata, the couple's family friend. Despite the overwhelming disadvantages in specs, Kanata makes it to the top 15 while racing top-tier supercars, demonstrating his phenomenal skills. Takumi Fujiwara, the legendary downhill and rally racer, turns out to be Kanata's trainer. MFG employees who are familiar with Fujiwara and former racers from the same generation begin to notice Kanata. A new whirlwind is about to set off at MFG.

Rikuo Nura, a part-youkai and part-human boy, grew up as the young master of the Nura Clan. Comprising youkai of all shapes and sizes, Rikuo treated the clan like family, however, he learned that he was the only one among his classmates who saw them in this light. To most, they were terrifying creatures of folklore who ate children and relished in bloodshed. Taking this to heart, he swore to live his life as a normal human. Normalcy, however, is hard to come by for young Rikuo. Complicating his goal are his youkai attendant, who under the name Tsurara Oikawa, goes to school alongside him; the young onmyouji Yura Keikain; and his close friend Kiyotsugu, who idolizes youkai and hopes to prove their existence. To make matters worse, rival youkai and other entities threaten to harm those Rikuo holds dear. If he wants to protect what's important to him, Rikuo must acknowledge his ancestry—that he is the grandson of the legendary Nurarihyon—and transform at night into a youkai, becoming worthy of being the next leader of the Nura Clan. [Written by MAL Rewrite]

In the land of Terra, natural disasters of unknown causes have been occurring irregularly in many areas. Therefore, the majority of the people, in order to escape those natural disasters, came to live in mobile cities developed over the years. The Originium left behind at the site of such Catastrophes, has led to the rapid progress of civilization due to their immense energy. But it also brought something else with it — an incurable disease called Oripathy. Because the bodies of those with Oripathy gradually crystalize and become a new source of infection at the time of death, in many countries, the Infected are subject to persecution under regimes of segregation and forced labor. Those who were oppressed by the governments are starting to rebel. Rhodes Island, a pharmaceutical company researching a cure for Oripathy, takes up their arms and starts a conquest trying to save all the people from the disease.

In the year 1930, vampires have infiltrated Tokyo to feast upon its unsuspecting citizens. As the number of victims continues to rise, the city's authorities decide to hire the Jaegers—a strange, diverse group of individuals tasked by the V Shipping Company to hunt down vampires around the world. Carrying musical instrument cases to disguise their identity, the Jaegers battle the vampires with the same mercilessness demonstrated by their foes. Yuliy, the Jaeger's most skilled warrior, is the sole survivor of a vampire raid on his home village. Using the strength granted by his werewolf blood, he works with his team to assist Tokyo's law enforcement with the city's vampire problem. Though under the pretense of helping the police, the Jaegers are actually fighting the vampires over the mystical Ark of Sirius. With its power to change the fate of the world, Yuliy and his friends must locate the artifact before the vampires can use it to achieve their destructive goals. [Written by MAL Rewrite]