Mahiru Shiina is worthy of her nickname "Angel": she is a divine beauty loved by all, and she excels in both academics and athletics. Shiina lives in an entirely different world from Amane Fujimiya, her next-door neighbor. Despite living so close together, they have never spoken once. But their silence is broken when Fujimiya spots Shiina gloomily sitting on a swing amidst a heavy rainstorm and lends her his umbrella. When Fujimiya catches a cold the next day, Shiina wishes to return the favor for the umbrella by nursing him back to health. Believing that this would be their first and last interaction, he silently appreciates her kindness. However, Shiina—who can not help but worry about Fujimiya's lack of tidiness and proper nutrition—begins to cook and clean for him. As the unlikely pair spend time together in Fujimiya's apartment, they explore the true nature of their relationship and the gentle emotions that emerge from it.

Dr. Kenzou Tenma, an elite neurosurgeon recently engaged to his hospital director's daughter, is well on his way to ascending the hospital hierarchy. That is until one night, a seemingly small event changes Dr. Tenma's life forever. While preparing to perform surgery on someone, he gets a call from the hospital director telling him to switch patients and instead perform life-saving brain surgery on a famous performer. His fellow doctors, fiancée, and the hospital director applaud his accomplishment; but because of the switch, a poor immigrant worker is dead, causing Dr. Tenma to have a crisis of conscience. So when a similar situation arises, Dr. Tenma stands his ground and chooses to perform surgery on the young boy Johan Liebert instead of the town's mayor. Unfortunately, this choice leads to serious ramifications for Dr. Tenma—losing his social standing being one of them. However, with the mysterious death of the director and two other doctors, Dr. Tenma's position is restored. With no evidence to convict him, he is released and goes on to attain the position of hospital director. Nine years later when Dr. Tenma saves the life of a criminal, his past comes back to haunt him—once again, he comes face to face with the monster he operated on. He must now embark on a quest of pursuit to make amends for the havoc spread by the one he saved. [Written by MAL Rewrite]

Since the death of his parents, Shinpei Ajiro had lived with the Kofune family and their two daughters—Mio and Ushio. Although he then left his home island to continue his education in Tokyo, Shinpei returns after Ushio tragically drowns during the attempted rescue of a little girl. During the funeral, his best friend informs him about bruises found around Ushio's neck, casting doubt over the cause of her death. Suspecting a murder has taken place, Shinpei reevaluates recent events, but strange incidents only continue to transpire. Disappearing people and other unexplainable occurrences lead Mio to recall an old folktale referring to entities called "Shadows," which may not be entirely fantasy. Supposedly, an encounter with one's Shadow foretells the person's impending demise. Facing the dark side of Hitogashima Island, Shinpei stands against his grim fate to fulfill Ushio's final will—to protect Mio.

In the wake of defeating Boros and his mighty army, Saitama has returned to his unremarkable everyday life in Z-City. However, unbeknownst to him, the number of monsters appearing is still continuously on the rise, putting a strain on the Hero Association’s resources. Their top executives decide on the bold move of recruiting hoodlums in order to help in their battle. But during the first meeting with these potential newcomers, a mysterious man calling himself Garou makes his appearance. Claiming to be a monster, he starts mercilessly attacking the crowd. The mysterious Garou continues his rampage against the Hero Association, crushing every hero he encounters. He turns out to be the legendary martial artist Silverfang’s best former disciple and seems driven by unknown motives. Regardless, this beast of a man seems unstoppable. Intrigued by this puzzling new foe and with an insatiable thirst for money, Saitama decides to seize the opportunity and joins the interesting martial arts competition. As the tournament commences and Garou continues his rampage, a new great menace reveals itself, threatening the entire human world. Could this finally be the earth-shattering catastrophe predicted by the great seer Madame Shibabawa? [Written by MAL Rewrite]