The story takes place in Japan. The year is 2030 and Earth has been completely overrun by a viral disease named "Gibia" that turns infected people into various different monsters, based on their age, sex, and race. A samurai and a ninja from the early Edo period travel together through time and arrive in a ruined Japan to aid a professor working on a cure for the virus. Together, they fight countless Gibia monsters, outlaws, and other fierce foes on their journey to save mankind.

A young girl named Zuru sets out on an expedition through a post-apocalyptic city controlled by machines in a desperate hunt for food. Things go awry when her team accidently triggers the city's AI defense program called the Safeguard. Attacked by the machines, her companions are on the verge of being annihilated when a mysterious man named Killy arrives and exterminates the hostile units.

Despite his heroic intervention, Zuru is hesitant to trust Killy and questions his motives. He reveals to have come from thousands of levels below the city in order to find humans possessing the Net Terminal Genes—a trait that would allow humans to regain control of their civilization and shut down the Safeguard. After hearing his story, Zuru and the rest of her team join Killy and embark on a journey in search of the Genes that could prove to be mankind's last hope of survival.

[Written by MAL Rewrite]

Traumatized by school, Jun Sakurada spends his days at home as a shut-in, purchasing things online, only to send them back before the free trial period ends. So when a note appears on his desk, asking whether or not he would wind something, he assumes it was something he ordered and carelessly circles "yes," changing his life forever. A box arrives with a wind up doll inside, but this is no ordinary toy: after Jun winds her up, she begins walking and talking as if a normal person. With a haughty attitude, she introduces herself as Shinku, the fifth doll in the Rozen Maiden collection, a group of special dolls made by the legendary dollmaker Rozen. These sisters must battle each other in a competition called the Alice Game with the help of a human to ensure victory. The winner becomes Alice, a real girl who is worthy of meeting their creator. As more sentient dolls end up taking residence in Jun's house, and a foe from Shinku's past makes her appearance, Jun's life becomes far more complicated than he ever thought possible. [Written by MAL Rewrite]

Iroe Genma is a third-year high school student often referred to as "Elder Sister" despite her short height. This troublemaking teenager is the president of her school's Model Club, which is dedicated to building plastic models of various objects and structures, such as cars, boats, and even robots. Joined by her two underclassmen, the violent Hazuki "Okappa" Okamoto and the rational Makina "Makimaki" Sakamaki, the small group aims to carry out their club duties but are often sidetracked by a myriad of distractions. From battles between club members to lessons on how to confess to your crush, these three schoolgirls get caught up in all sorts of wacky, and downright outrageous situations!