In the 21st century, the rapid development of the human society has broken the equilibrium between the realms of human, immortal and monster. Su Moting is an ordinary working girl living in the human world. She is also the "son of the immortal and the monster". Driven away from home by her parents, Su teams up with an immortal and a monster, and the three of them start their hilarious daily life.

Continuing right where season 1 left off: Harima still likes Tenma but still runs into obstacles everytime he tries to confess his love to her. To complicate the situation, Class 2-D challenges class 2-C once again and there's a rumor floating around that Harima and Yakumo are dating as the school prepares for the cultural festival. (Source: ANN)

With his mother taken away from him and having lost everything, Lag Seeing is now a letter whose delivery has been assigned to Gauche Suede, a Letter Bee. Despite their troubling start, the two of them become friends, leading Lag to realize what his aim in life is: to deliver people's most important feelings in the form of letters, just as Gauche has done. [Written by MAL Rewrite]

Humans live their lives driven by ambition and greed, prepared to kill their own kind with no hesitation. Since the beginning of humanity, wars have raged on throughout the human world, with the other races watching on. A victim of one war and orphaned, Ashleen was saved by the lord of the werewolves, Muzaka. Muzaka had abandoned his duties as lord and left the werewolf clan, travelling with Ashleen to secure her happiness. However, during his absence, members of Muzaka's species began orchestrating further wars on humans, disgusted by Muzaka's compassion. A secret and powerful organization established itself in the human realm, intending to manipulate Muzaka. When he is misinformed by the Union, Muzaka starts directing his rage toward the humans. Can his only friend, Cadis Etrama Di Raizel, the Noblesse, stop Muzuka's madness? Set 820 years before the events of Noblesse, Noblesse: Pamyeol-ui Sija depicts the tragic history of Muzaka, and how it led to the Noblesse's indefinite slumber.