The world of psychology is far from strange to the unusual Dr. Ichirou Irabu, a resident psychiatrist of Irabu General Hospital. He and his charming nurse Mayumi run through several patients, each suffering from a mental illness that harms their everyday life. Patients should be wary of the seductive Mayumi, with her spellbinding looks and devilishly short pink nurse uniform. On the other hand, the doctor seems to have three separate personalities: a child with an oversized lab coat; an intelligent, youthful man with feminine traits; and a selfish, outgoing green bear. While curing his patients in questionable ways, Dr. Irabu often tries to gain something from them outside of his profession—and in doing so, occasionally forgets his role as a doctor. As each patient struggles to face the nature of their distress, an obvious yet invisible thread ties their paths together.

With the ensemble contest behind them, the members of the Kitauji High School concert band now aim to win a gold medal at the national competition. For third-year club president Kumiko Oumae and her friends, it is their last chance before graduation. Filled with anticipation and anxiety, Kumiko worries if she can successfully lead the band. Amid her struggles, Kumiko encounters transfer student Mayu Kuroe. From her gentle demeanor to her talented euphonium skills, Mayu was a member of the Seira Girls' School concert band—a regular at nationals. While Mayu is friendly, Kumiko cannot help but have an indescribable feeling from their meeting. As new members arrive and plans are set in motion, the club, with an insatiable hunger for a gold medal, learns what it truly takes to propel themselves to reach the national level.

Having bid farewell to his former teammates at Kaido High School's baseball club, Gorou Honda returns to his hometown eager to continue playing. Attending a new high school proves to be more difficult than he initially expected, as Tetsufumi Egashira's merciless slandering of his name prevents Gorou from being accepted into any school with an existing baseball team. Left with no other options, Gorou joins Seishuu High School, where his childhood friend Kaoru Shimizu also attends. However, Seishuu has always been an all-girls school until two years ago, so there is not yet a dedicated men’s baseball team. But nothing will stop Gorou in his pursuit of Koshien. He must now create a baseball team from scratch with the seven male students at Seishuu, but all of them are complete amateurs! He decides to train the incompetent team up to nationally competitive levels, but such a feat is easier said than done. Will Gorou once again perform miracles? Or will he give up on achieving his goal of defeating Kaido with his own team? [Written by MAL Rewrite]

Following the line of the precedent OVAs (of the same name) This anime goes around the normal lives of some elementary school (5th grade, 2nd class room) kids and their adventures, while turning to teens. Their games, stupid jokes, and the misunderstandings around their premature attraction to the opposite sex. Ryota Satou is the main character here, but his friends are almost as important as him since the school wouldn't be the same without them, especially the girls who the majority of time appear to be mature by their ages but in the ends they are as childish and even more "dangerous" than the boys. (Source: ANN, edited)