Kazuya Kinoshita is a 20-year-old college student who has a wonderful girlfriend: the bright and sunny Mami Nanami. But suddenly, he doesn't. Without warning, Mami breaks up with him, leaving him utterly heartbroken and lonely. Seeking to soothe the pain, he hires a rental girlfriend through an online app. His partner is Chizuru Mizuhara, who through her unparalleled beauty and cute demeanor, manages to gain Kazuya's affection. But after reading similar experiences other customers had had with Chizuru, Kazuya believes her warm smile and caring personality were all just an act to toy with his heart, and he rates her poorly. Aggravated, Chizuru lambastes him for his shameless hypocrisy, revealing her true pert and hot-tempered self. This one-sided exchange is cut short, however, when Kazuya finds out that his grandmother has collapsed. They dash toward the hospital and find Kazuya's grandmother already in good condition. Baffled by Chizuru's presence, she asks who this girl might be. On impulse, Kazuya promptly declares that they are lovers, forcing Chizuru to play the part. But with Kazuya still hung up on his previous relationship with Mami, how long can this difficult client and reluctant rental girlfriend keep up their act? [Written by MAL Rewrite]

World-class medical researcher Kanji Yakutani lost his little sister to a tumor years ago due to ineffective treatment. To honor her legacy, he has dedicated his research to developing new medications for such conditions. But as fate would have it, he overworks himself and passes away at the age of 31, only to be given a second chance at life in another world. When he wakes up, Kanji finds himself in the body of a 10-year-old boy named Falma de Médicis, the son of an esteemed family of medical practitioners in the Sain Fleuve Empire. Bearing the mark of a deity's divine blessing, Falma is capable of performing a unique divine art, allowing him to create and reduce any substance with the knowledge of its chemical properties. After reading through some pharmacology books, Falma realizes that this world is operating on similar medical practices as in ancient times. He also learns that medicine is an exclusive privilege to the nobility, depriving commoners of proper medical care. Using the knowledge from his past life and the divine abilities granted to him, Falma resolves to make medicine available to those who need it—irrespective of class.

Listless geek Mizuto Irido and introverted nerd Yume Ayai seemed like a match made in heaven, connected by their mutual love for literature. Unfortunately, their differences gradually grew, and they separated just after their middle school graduation. But, as if by divine comedy, the two find themselves reunited as step-siblings. A rivalry begins to brew between the former couple, both unwilling to acknowledge the other as the older sibling. In an attempt to "solve" this issue, Mizuto and Yume agree upon a rule: whoever crosses the boundaries of siblinghood norms loses, and the winner will not only be called the older sibling, but also get to make a request. However, now that they live under the same roof, the lingering memories they share start to influence their actions—possibly rekindling the feelings that may not have been fully extinguished in the first place.

Unlike his friends, Takumi Fujiwara is not particularly interested in cars, with little to no knowledge about the world of car enthusiasts and street racers. The son of a tofu shop owner, he is tasked to deliver tofu every morning without fail, driving along the mountain of Akina. Thus, conversations regarding cars or driving in general would only remind Takumi of the tiring daily routine forced upon him. One night, the Akagi Red Suns, an infamous team of street racers, visit the town of Akina to challenge the local mountain pass. Led by their two aces, Ryousuke and Keisuke Takahashi, the Red Suns plan to conquer every racing course in Kanto, establishing themselves as the fastest crew in the region. However, much to their disbelief, one of their aces is overtaken by an old Toyota AE86 during a drive back home from Akina. After the incident, the Takahashi brothers are cautious of a mysterious driver geared with remarkable technique and experience in the local roads—the AE86 of Mount Akina. [Written by MAL Rewrite]