Nicholas Brown and Worick Arcangelo, known in the city of Ergastalum as the "Handymen," are mercenaries for hire who take on jobs no one else can handle. Contracted by powerful mob syndicates and police alike, the Handymen have to be ready and willing for anything. After completing the order of killing a local pimp, the Handymen add Alex Benedetto—a prostitute also designated for elimination—to their ranks to protect her from forces that want her gone from the decrepit hellhole of a city she has come to call home. However, this criminal’s paradise is undergoing a profound period of change that threatens to corrode the delicate balance of power. Ergastalum was once a safe haven for "Twilights," super-human beings born as the result of a special drug but are now being hunted down by a fierce underground organization. This new threat is rising up to challenge everything the city stands for, and the Handymen will not be able to avoid this coming war. [Written by MAL Rewrite]

In the series, Light and Yomi are spending their daily lives happily playing video games. One night when everyone else is asleep, Light receives an invitation from Alpha, a messenger for someone named King. Light and Yomi are then sucked into another world, where they must undertake a quest to rescue Princess Melody from the demon lord. Light thinks this must be his destiny, while Yomi thinks it's kind of annoying. They form a party with Alpha to start their quest. Alpha as it turns out is an AI robot, and he has a program that allows them to raise their levels while slowly continuing their adventure. (Source: ANN)

In early 1900s Hokkaido after the Russo-Japanese war, Saichi Sugimoto tirelessly pans for gold. Nicknamed "Sugimoto the Immortal" for his death-defying acts in battle, the ex-soldier seeks fortune in order to fulfill a promise made to his best friend before he was killed in action: to support his family, especially his widow who needs treatment overseas for her deteriorating eyesight. One day, a drunken companion tells Sugimoto the tale of a man who murdered a group of Ainu and stole a fortune in gold. Before his arrest by the police, he hid the gold somewhere in Hokkaido. The only clue to its location is the coded map he tattooed on the bodies of his cellmates in exchange for a share of the treasure, should they manage to escape and find it. Sugimoto does not think much of the tale until he discovers the drunken man’s corpse bearing the same tattoos described in the story. But before he can collect his thoughts, a grizzly bear—the cause of the man's demise—approaches Sugimoto, intent on finishing her meal. He is saved by a young Ainu girl named Asirpa, whose father happened to be one of the murdered Ainu. With Asirpa's hunting skills and Sugimoto's survival instincts, the pair agree to join forces and find the hidden treasure—one to get back what was rightfully her people's, and the other to fulfill his friend's dying wish. [Written by MAL Rewrite]

In Hokkaido, it is rumored that there is a stash of hidden gold. This gold was supposedly stolen by a man who killed the original Ainu owners; and before being captured and imprisoned by the police, he hid it in a secret location. In order to relay the gold's location to his comrades on the outside, he tattooed the map on the bodies of his cellmates and promised them a share of the gold—provided they managed to escape and find it. In Golden Kamuy 2nd Season, First Lieutenant Tokushirou Tsurumi plans to give the 7th Division an advantage in the war for the tattoos by getting a taxidermist to create skins that only he can distinguish as fake. Meanwhile, Saichi "The Immortal" Sugimoto, Asirpa, and their companions continue their hunt for the skins by following a strange rumor: a thief who broke into a home in Yubari found taxidermied human corpses, among which was a torso with strange tattoos. [Written by MAL Rewrite]