Kaoruko "Chaos" Moeta is a young manga artist who is down on her luck. She wants to draw manga about high school girls, but her storyboards are bland, her art uninspired, and her premises weak. Her concerned, exasperated editor comes up with an idea: push Chaos to be more social. So, by her recommendation, Chaos moves into a dormitory for female manga artists. She soon meets the other residents: Tsubasa Katsuki, a shounen manga artist; Ruki Irokawa, who draws erotic manga popular with women; and Koyume Koizuka, a shoujo artist who, like Chaos, has yet to be serialized. Quickly striking up a friendship with these girls, Chaos finds new inspiration for her manga and continues to grow her creativity. Comic Girls is a showcase of the daily lives of these manga artists. Will Chaos finally be able to make her debut and become serialized? None of the girls know, but they will all do their best to help each other become the best artists they can be. [Written by MAL Rewrite]

It is widely believed that science can provide rational explanations for the countless phenomena of our universe. However, there are many aspects of our existence that science has not yet found a solution to and cannot decipher with numbers. The most notorious of these is the concept of love. While it may seem impossible to apply scientific theory to such an intricate and complex emotion, a daring pair of quick-witted Saitama University scientists aim to take on the challenge. One day the bold and beautiful Ayame Himuro outwardly declares that she is in love with Shinya Yukimura, her fellow logical and level-headed scientist. Acknowledging his own lack of experience with romance, Yukimura questions what factors constitute love in the first place and whether he is in love with Himuro or not. Both clueless in the dealings of love, the pair begin to conduct detailed experiments on one another to test the human characteristics that indicate love and discern whether they demonstrate these traits towards each other. As Himuro and Yukimura begin their intimate analysis, can the two scientists successfully apply scientific theory, with the help of their friends, to quantify the feelings they express for one another? [Written by MAL Rewrite]

Keitaro has finally passed the entrance exams, and is officially a Toudai student. But after breaking his leg in an accident in the entrance ceremony, he thought and re-evaluated himself. Having new goals, Keitaro follows Seta on an overseas archeology trip. During his absence, however, all was not well in Hinata Lodge. Urashima Kanako, Keitaro's sister, arrives on the scene. She claims to be the new manager of Hinata Lodge starts to go against all the tenants. Things become even more complicated when they recieve a letter from Keitaro. The tenants and Kanako made a big mess trying to get the letter, but Seta's car crashes in before anyone could read the letter...

Maeda Toshiie and Matsu visit Chousokabe Motochika, who governs Shikoku. They tell Motochika unreasonable demands from Nobunaga. Motochika rejects them and urges Maeda to betray Nobunaga. Meanwhile Keiji tries to convince Mouri Motonari to join the fight against Nobunaga, and is imprisoned as a result. Motochika and Motonari move against each other.