Although traumatized by witnessing the murder of his parents by one of the Choushuu, Ichimura Tetsunosuke's thirst for revenge lead him to desire strength. At the age of 15, Tetsunosuke approached the Shinsengumi, wanting to become one of its members. However, Tetsunosuke lacked the skill, mind and will to emotionlessly cut down whoever threatened peace and the Shinsengumi. Even with the support of his brother Tatsunosuke and his newfound friends of the Shinsengumi, little did Tetsunosuke know the blood and pain he would have to face being part of this historical group.

The main character, a cat named Nyatto, embarks upon a journey to save his sister's soul, which was ripped in two when Nyatto tried to save her from Death. She trails after him, brain-dead. They encounter many brilliant, mind-bending situations, beginning with a disturbing magic show.

Immortality is something many people would wish for. But would it be such a coveted ability if people knew they would be subject to countless attacks because of it? Such is the case for Rin Asougi, an immortal private investigator, because there is no shortage of people who want her dead. Over the centuries, she has met many grisly ends, but each time, she returns to life as if nothing had happened. In 1990, while looking for a lost cat, Rin runs into Kouki Maeno, a man who feels that his memories are wrong. Agreeing to help him, Rin discovers that Kouki is not what he seems, all the while drawing closer to her true enemy. This adversary knows Rin and her kind all too well, and if she dies by his hand, she may stay dead permanently. [Written by MAL Rewrite]

Kouichi Sanada and Kazuki Aihara's childhood friend Mao Mizusawa has returned after living in France for a couple of years. Kouichi is surprised to learn that, since her parents are remaining overseas for the time being, his mother has agreed to let Mao stay with them. The three friends help each other deal with the ups and downs of high school romance.