In Edo in the mid-1800's, fireworks maker Seikichi Tamaya and his friends struggle to live under the harsh morality laws imposed by the strict city councilor, which ban all luxuries, including fireworks. One day, a strange girl stops by Sekichi's shop with an equally strange request: she wants Sekichi to build a firework that can reach the moon.

Fifty years ago, horrific creatures dubbed as the "enemies of humanity" suddenly appeared around the world. To combat these threats, teenagers gifted with supernatural abilities called "Talents"—such as pyrokinesis and time travel—hone their powers at an academy on a secluded island. Nanao Nakajima, however, is quite different from the others on the island: he has no Talent. With many "Talented" teenagers around him, Nanao is often a target for bullying, but even so, he still strives to complete his training. Soon after, two transfer students, the mysterious Kyouya Onodera and the mind-reading Nana Hiiragi, join the class. But just as everyone starts blending as comrades-in-arms, mysterious disappearances begin to threaten the class's entire foundation. [Written by MAL Rewrite]

In 18th century Paris, a coffin is found floating down the Seine River. It carries the corpse of noblewoman Lia de Beaumont: a spy of King Louis XV, and whose younger brother Charles d'Eon has just been knighted. When several disappearances occur throughout Paris, the young knight believes that they are somehow connected to his sister's death. Hoping to find her killers, d'Eon joins the secret police to investigate the incidents. Following the clues, they piece together that a conspiracy between members of the French and Russian nobility, spurred on by a cult, may be behind the disappearances. D'Eon concludes that Lia may have uncovered the truth while on a mission and was killed as a result. That night, the secret police are to arrest the Duke of Orléans on suspicion of being the mastermind. One of their own transforms into a demon called a Gargoyle and massacres the group. D'Eon attempts to rescue the sole survivor, only to find that he too has been transformed. During the ensuing battle, d'Eon is possessed by Lia's vengeful soul, who takes command of his body and slays the Gargoyle herself. In the aftermath, d'Eon must gather allies to discover the depth of this supernatural conspiracy. [Written by MAL Rewrite]

Following the line of the precedent OVAs (of the same name) This anime goes around the normal lives of some elementary school (5th grade, 2nd class room) kids and their adventures, while turning to teens. Their games, stupid jokes, and the misunderstandings around their premature attraction to the opposite sex. Ryota Satou is the main character here, but his friends are almost as important as him since the school wouldn't be the same without them, especially the girls who the majority of time appear to be mature by their ages but in the ends they are as childish and even more "dangerous" than the boys. (Source: ANN, edited)