Nanako is a an inept apprentice nurse to the brilliant young Dr. Kouji. Now for some reason, Nanako is always being targeted by various elements which makes Nanako wonder if she has done anything wrong. But there are certain secrets to Nanako's past that only Dr. Kouji and his family know about.

The forces of evil are on the rise. When the evil mastermind Sister Jill transforms one of her girls into the bestial Breast Claw and sends her minions out on a mission involving the group Panther Claw and a jewelry store heist, Honey Kisaragi departs from her Catholic girls' school to confront the threat as Cutie Honey. But that's exactly what Sister Jill wants, as she desires Honey's Airborne Element Fixing Device, which allows her to transform into Honey's seven different forms. Meanwhile, Sister Jill is also on the scene in disguise as Inspector Genet, trying to worm her way into Honey's confidence from a different angle. (Source: ANN)

In the year Future Century 0060, the many countries that once comprised Earth's surface exist as separate colonies floating in space. Their home planet now uninhabitable, the ruler of all of the colonies is decided by their unanimous participation in the intergalactic Gundam Fight Tournament—a series of battles between the champions of each colony to determine who is most fit to reign over them all. Neo-Japan's champion is Domon Kasshu, a man who accepts the role with some ulterior motives. Domon searches the galaxy for his brother, a criminal who allegedly murdered their mother and made off with the Devil Gundam, a highly advanced weapon with the power to unleash mass destruction across the galaxy. In his quest to bring his sibling to justice, Domon travels from colony to colony, meeting many of the fighters who will become his allies and enemies in the forthcoming Gundam Fight Tournament. Armed with the strength of the Shining Gundam, Domon battles to uncover the truth behind his tortured childhood, suffering great betrayal and crushing blows on his quest toward personal and national triumph. [Written by MAL Rewrite]

Anime adaptation of the spin-off manga that stars the black-silhouetted "criminal" that appears in representing the mystery culprits.