Hole—a dark, decrepit, and disorderly district where the strong prey on the weak and death is an ordinary occurrence—is all but befitting of the name given to it. A realm separated from law and ethics, it is a testing ground to the magic users who dominate it. As a race occupying the highest rungs of their society, the magic users think of the denizens of Hole as no more than insects. Murdered, mutilated, and made experiments without a second thought, the powerless Hole dwellers litter the halls of Hole's hospital on a daily basis. Possessing free access to and from the cesspool, and with little challenge to their authority, the magic users appear indomitable to most—aside for a few. Kaiman, more reptile than man, is one such individual. He hunts them on a heedless quest for answers with only a trusted pair of bayonets and his immunity to magic. Cursed by his appearance and tormented by nightmares, magic users are his only clue to restoring his life to normal. With his biggest obstacle being his stomach, his female companion Nikaidou, who runs the restaurant Hungry Bug, is his greatest ally. Set in a gritty world of hellish design, Dorohedoro manages a healthy blend of comedy and lightheartedness with death and carnage. Taking plenty of twists and turns while following the lives of Hole's residents, it weaves a unique world of unearthly origin and dreary appearance not for the squeamish or easily disturbed. [Written by MAL Rewrite]

A goldfish sneaks away from home and floats off on the back of a jellyfish. After getting stuck in a glass jar, she drifts to the shore where she is freed by Sousuke, a five-year-old boy who lives with his mother Lisa in a house by the sea while his father Koichi works on a fishing boat. After healing a cut on Sousuke's finger by licking it, the goldfish is named Ponyo by her new friend.

Unknown to Sousuke, Ponyo already has a name and a family. Her father Fujimoto, a sorcerer who forsook his humanity to live underwater, searches frantically for his daughter Brunhilde. When found and captured, Ponyo rejects her birth name and declares that she wants to become a human. Using the power received from Sousuke's blood, she grows arms and legs and escapes to the surface once more. But the magic released into the ocean causes an imbalance in nature, causing the Moon to start falling out of orbit and the tides to grow dangerously stronger. Reunited with Ponyo, Sousuke must pass an ancient test to restore order in the world and let his companion live on as a human.

Ryouta Sakamoto is unemployed and lives with his mother, his only real achievement being that he is Japan's top player of the popular online video game Btooom! However, his peaceful life is about to change when he finds himself stranded on an island in the middle of nowhere, with a small green crystal embedded in his left hand and no memory of how he got there. To his shock, someone has decided to recreate the game he is so fond of in real life, with the stakes being life or death. Armed with a bag full of unique bombs known as "BIM," the players are tasked with killing seven of their fellow participants and taking their green crystals in order to return home. Initially condemning any form of violence, Ryouta is forced to fight when he realizes that many of the other players are not as welcoming as they may seem. Teaming up with Himiko, a fellow Btooom! player, they attempt to get off of the island together, coming closer and closer to the truth behind this contest of death. [Written by MAL Rewrite]

Short specials included in the Blu-ray and DVD releases.