Tousuke Rokudou is a first-year attending Aomori High, a school full of delinquents. He is often bullied by his classmates due to his incompatibility with their behavior, the only exceptions being his two good friends who are also social outcasts. Frustrated at the way they are treated, the three wish they could stand up and claim the fun, peaceful school life of their dreams. However, Tousuke's life takes a drastic turn when he receives a package from his late grandfather containing their family heirloom, a scroll said to possess the power to save him from impending danger. Upon holding the scroll, a sudden glow emanates, leaving a strange mark on Tousuke's forehead. Thinking that he's received the means to free himself and his friends from their daily treatment, Tousuke is shocked to find out that its effects are far different than what he had imagined. Although his bullying continues, he realizes that the mark from the scroll acts as a charm, capturing the hearts of delinquent girls—in particular, Ranna Himawari, the strongest of them all.

After a successful showdown at Tokyo Tower, the Mew Mew girls enjoy a temporary respite. Now that Ichigo Momomiya and Masaya Aoyama have confessed their feelings to each other, Ichigo is overjoyed to spend time with her new boyfriend. However, their quick break gets interrupted, and soon the girls must battle against the Chimera Anima yet again. When things go awry in the ensuing fight, Ichigo is placed in grave danger. Just when things look most bleak, the mysterious Blue Knight arrives and saves Ichigo, proclaiming that he was born to protect her, before disappearing into thin air. With the fate of the world on their shoulders and the identity of the Blue Knight in question, the Mew Mew girls must strive to create balance between alien-fighting and their personal lives.

Foolhardy police officer Brian Nightraider is dismissed from the force for a history of reckless behavior that ultimately resulted in his partner's death. While wallowing in self-pity, the disgraced officer receives a curious invitation from the United Nations Immigration Bureau Special Investigation Unit. He has been recruited to join the Marginal Service, a secret underground branch of the UN tasked with handling Borderlanders. Indistinguishable from humans, Borderlanders are aliens that peacefully coexist in society. But now, a Borderlander terrorist organization has emerged, manufacturing and distributing a potent drug called Confu. With the Borderlanders' ability to regenerate and blend in as humans, uncovering the drug-trafficking ring will be no easy undertaking. However, the ragtag group at the Marginal Service are not one to back down from a challenge—even as their work exposes some unexpected figures as Borderlanders.

For more than four hundred years, the Takamimi Shrine has stood in Tokyo, enshrining the local goddess: Elda, a magical elf summoned from another world. The immortal elf has been served for 15 generations by the family who summoned her in the Edo period. Now, after Koito Koganei turns 16 years old, this responsibility falls onto her. Serving as Elda's shrine maiden, Koito must balance her responsibilities with her daily school life. This proves to be difficult because Elda is a total social recluse who loves video games, collecting toys, and eating snacks. In an effort to get the lazy shut-in to experience more of the outside world, Koito juggles her time between indulging Elda's various hobbies and getting her to interact with the rest of humanity. Along the way, Koito learns more about the history of the area and what makes the goddess so loved and spoiled by the locals.